Nascent polypeptide chains or polypeptidyl-tRNAs (pep-tRNAs) occur transiently during protein synthesis. The potential to study these intermediates and better understand their role in processes like ...

Transcription and translation are processes a cell uses to make all proteins the body needs to function from information stored in the sequence of bases in DNA. The four bases (C, A, T/U, and G in the ...

For years, ETH researchers have been investigating a molecular complex that plays a key role in protein synthesis. They have ...

Imagine a breakthrough in cancer treatment where only malignant cells are targeted, sparing healthy host cells; or patients with abnormal protein synthesis are treated to produce a healthy protein.

More than a century ago, the anatomist Santiago Ramón y Cajal unveiled his incredibly detailed drawings of neurons. From these, he posited that neurons were the main building blocks of the brain and ...

The innate immune protein C1q seems to have a thing for neurons. Already implicated in synaptic pruning by microglia, now it is reported to also slow down protein production in neurons of the aging ...

Aging selectively impairs the production of crucial DNA- and RNA-binding proteins, which contributes to hallmarks of aging in the brains of killifish, according to a new study. The findings advance ...

Imagine a cancer treatment that precisely targets malignant cells, leaving healthy ones untouched. Consider, also, a cancer treatment that corrects abnormal protein synthesis to produce healthy ...