The regulation of the cell cycle is a fundamental process ensuring the accurate replication and division of cells. Central to this regulation are the Cdc25 phosphatases, which activate ...

TGFβ/ACTIVIN-SMAD2/3-EZH2 cooperates with OCT4 and NANOG in self-renewing hPSCs to keep CDKIs in an epigenetically poised state for rapid activation. Upon the initiation of endoderm differentiation ...

The awe-inspiring process of cell division can turn a fertilized egg into a baby -- or a cancerous cell into a malignant tumor. With so much at stake, nature keeps it tightly controlled in a process ...

The field of immunology of ageing is rapidly evolving, with T cells playing a pivotal role in maintaining immune competence and overall organismal ...