Inflammation covertly rewires the bone marrow, enabling mutated stem cells to rise and setting the stage for future blood disease.

The tumor microenvironment (TME) consists of mediators surrounding a tumor, including diverse cell types, blood vessels, and ...

Various tissues and organs in the human body, such as nerves, heart, bones, and skin, rely on bioelectrical signals to maintain function and support ...

The immune system is the body’s first line of defense when it comes to fighting cancerous cells. It can identify and attack the smallest of threats before they become a danger, and distinguish tumor ...

Chronic circadian disruption — such as night-shift work, irregular schedules, or frequent jet lag — accelerates the ...

Chimeric antigen receptor T (CAR-T) cell therapy has revolutionized hematologic cancer treatment, but its efficacy in solid tumors remains limited by poor infiltration into the complex tumor ...

Cancer cells don’t exist in isolation – instead, they live within a complex ecosystem that also includes immune cells, stromal cells, the extracellular matrix, blood vessels and many other factors.

The landscape of breast cancer research is undergoing a significant shift, moving toward complex, combination strategies designed to overcome the body’s own immune suppression.

Tumors are often considered to be malignant cells that operate independently of their environment; however, this is not the case. They are entities that negatively impact their surrounding environment ...