Researchers at Karolinska Institutet in Sweden have used DNA origami, the art of folding DNA into desired structures, to show how an important cell receptor can be activated in a previously unknown ...

Perhaps complex at first glance, in reality synNotch receptors function simply and possess unseen therapeutic potential. SynNotch is a synthetically engineered version of Notch, a receptor protein ...

The Notch signaling system links cellular fate to that of its neighbors, driving proliferation, apoptosis, and cell differentiation in metazoans, whereas dysfunction leads to debilitating ...

(Nanowerk News) Researchers at Karolinska Institutet have used DNA origami, the art of folding DNA into desired structures, to show how an important cell receptor can be activated in a previously ...

Chimeric antigen receptor (CAR) T cell therapy is a promising immunotherapy against cancer. The idea is to fortify a person’s immune system to fight its own battle by boosting T cells with the ability ...

Researchers have used DNA origami, the art of folding DNA into desired structures, to show how an important cell receptor can be activated in a previously unknown way. The result opens new avenues for ...

The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...

A pilot study on the anticancer effects of novel candidate agent COH-SR4 in lung cancer. This is an ASCO Meeting Abstract from the Markers in Cancer. This abstract does not include a full text ...

These papers were selected from multiple disciplines from the Faculty of 1000, a Web-based literature awareness tool http://www.facultyof1000.com N. Gupta-Rossi et al ...